The goal of the Lab is to develop new treatments and work towards a cure for epilepsy and other neurodevelopmental disorders using a range of innovative approaches in experimental systems.
The Lab studies mechanisms of cerebral cortical circuit function and circuit dysfunction in neurodevelopmental disorders. Investigators in the lab use mouse and human genetics, electrophysiology, pharmacology, imaging, optogenetics, and behavior, in a range of experimental model systems ranging from heterologous cells in culture, neurons generated from induced pluripotent stem (iPS) cells from human patients, and ex vivo and in vivo in animal models of human disease. The lab is particularly interested in the function of a prominent subtype of neuron known as the GABAergic inhibitory interneuron and the role of interneuron dysfunction as a cause of disease.
News from the Lab
The Goldberg lab welcomes its new members: Jerome Clatot. Research Scientist I. Demetrius Lee. Research Technician II. Ala Somarowthu. Postdoctoral Fellow. Guojie Qu. Postdoctoral Fellow.
Ethan is the recipient of the 2018 Dana Foundation David Mahoney Neuroimaging Grant to study mechanisms of seizure generation in an experimental model of Dravet Syndrome using in vivo two-photon calcium imaging. https://www.dana.org/Media/GrantsDetails.aspx?id=131972...
Kevin Goff attends the Ion Channels in Synaptic and Neural Circuit Physiology at Cold Spring Harbor Laboratory
June 5 – 25, 2018