The goal of the Lab is to develop new treatments and work towards a cure for epilepsy and other neurodevelopmental disorders using a range of innovative approaches in experimental systems.
The Lab studies mechanisms of cerebral cortical circuit function and circuit dysfunction in neurodevelopmental disorders. Investigators in the lab use mouse and human genetics, electrophysiology, pharmacology, imaging, optogenetics, and behavior, in a range of experimental model systems ranging from heterologous cells in culture, neurons generated from induced pluripotent stem (iPS) cells from human patients, and ex vivo and in vivo in animal models of human disease. The lab is particularly interested in the function of a prominent subtype of neuron known as the GABAergic inhibitory interneuron and the role of interneuron dysfunction as a cause of disease.
News from the Lab
Congrats, Sophie Liebergall!
Sophie Liebergall's paper is out in print!Ndnf Interneuron Excitability Is Spared in a Mouse Model of Dravet Syndromehttps://doi.org/10.1523/JNEUROSCI.1977-23.2024
Congrats, Melody & Eric!
Melody Cheng (School of Arts & Sciences '26) has been awarded a 2024 College Alumni Society Undergraduate Research Grant in the amount of $1,000. Congratulations to Melody and her postdoc mentor Eric Wengert.
Congrats, Clara!
Clara Wang (School of Arts & Sciences '25) has been awarded the prestigious Frances Velay Fellowship, to encourage and advance women in the sciences through summer undergraduate fellowships. This Fellowship provides $5,000 for summer research. Congratulations to Clara...